Basics of Cleanroom Design - Using the New ISO 14644-4, ISO 14644-16, and IEST-RP-CC012.4

Learn the basics of cleanroom design, using the new ISO 14644-4, ISO 14644-16, and IEST-RP-CC012.4.  Additional details noted in the course outline.

Course outline     Course materials     Who Should Attend     Instructor     Next date and location     Pricing

Course outline

  1. Cleanroom Basic Design Considerations
    1. ISO classifications and standards
    2. US cleanroom design guides and testing standard
    3. Particle sources
    4. Contaminants (particle, microbial, and chemical gas)
    5. Optimization of workflow/paths in existing cleanroom spaces
    6. Airflow quantity, flow pattern, and floor arrangement
    7. Schematics and airflow diagrams, room pressure settings, and room air balance, and pressurization plan
    8. Ventilation effectiveness and contaminant removal effectiveness
    9. Cleanroom structures and architecturals construction materials
    10. Basic HVAC, plumbing, fire protection, and process systems
    11. Performance testing and performance monitoring
  2. Compliances of ISO 14644-4, ISO 14644-16 Standards and Applications of RP-CC012.4 Recommended Practice
    1. Integrity of building envelope and interstitial spaces to prevent insects/pests entry
    2. Cleanroom enclosure airtightness
    3. Room pressure control
    4. Airlock categories, flow diagrams, and applications
    5. Grounding and structure design to avoid ESD and minimize EMI
    6. Computational Fluid Dynamics (CFD) to analyze airflow patterns and particle movements
    7. Airflow rate modeling
    8. Automatic or manual system control to achieve the required airflow rate and airflow direction, between rooms and pressure cascades.
    9. Demand flow control to conserve fan energy
    10. Variable flow cleanrooms with stable room temperature, humidity, and pressure controls
    11. Real-time continous performace monitoring and trend analysis
    12. Autonomous computer control of cleanroom ISO cleanliness class

Course materials

  • Copy of IEST-RP-CC012.4: Cleanroom Design
  • Copy of PowerPoint presentation in course binder

Continuing Education Units: .6 CEUs


Wei Sun

Wei Sun served as IEST Society President in 2016-2017, and Technical Vice President (Contamination Control) in 2013-2016, he has been the chair of WG-CC012 that is responsible for the new edition of RP-CC012.3 (Considerations in Cleanroom Design), and now leading the group working on the new RP-CC012.4 Edition. 

Sun also has served as the Chair of ASHRAE Technical Committee TC9.11 (Clean Spaces) from 2007 to 2010, a voting member of ASHRAE TC9.10 (Laboratory Systems) and TC9.6 (Healthcare Facilities). He is an ASHRAE Fellow and an ASHRAE Distinguished Lecturer since 2008. In addition to his design expertise for large cleanroom, lab, and healthcare projects; he has been serving as a Principal Investigator for many governmental research projects, over a dozen of technical articles have been published. Recently he published a new technical book (426 pages) called “ASHRAE Design Guide for Cleanrooms”.

Furthermore, Sun is an ISO 14644 standards’ USA delegate for Working Group 4 (cleanroom design and construction) and Working Group 16 (energy conservation in cleanrooms). Sun recently has been serving as the chairperson of NEBB’s Cleanroom Performance Testing (CPT) Standard Committee and developing a new cleanroom testing standard for NEBB.       

He has been invited to provide numerous technical speeches and training courses for private US industries, governmental agencies, national, and international conferences.

Who should attend?

I need to learn more about cleanroom HVAC systems because:

  • I am a cleanroom design engineer from an architectural or engineering firm
  • I am a cleanroom design/build contractor
  • I am a cleanroom research professional
  • I am a cleanroom product sales engineer
  • I am a cleanroom facility engineer/manager
  • I am a cleanroom quality control engineer/manager


Next date and location

January 25, 2024
9 a.m. - 4 p.m. CT

Early-bird discount ends December 8. Use coupon code 24BCD3EB to save 10%

Registration Information

Register three attendees from your company for the same training course and receive a complimentary fourth registration for another person in your company to attend that course. Contact IEST at 847-981-0100 to arrange this option. (Complimentary registration applies to registration of equal or lesser value. Not valid with any other offers or promotions.)

(Closes 1/22)
(After 1/22 if space permits)


IEST reserves the right to cancel course(s), in which case registrants will receive a refund of the fee. IEST is not responsible for any refund or remuneration for hotel, transportation, additional registration fees, tours, or other expenses related to attendance beyond the registration fee refund.

All orders must be paid in full at the time the order is processed. IEST does not invoice or accept purchase orders as payment. IEST reserves the right to charge a 5% administrative fee on additional transactions arising from customer order errors and a $40 fee for non-sufficient fund checks or credit card charge claims in error.

Transfers: Registrations are transferable to another person for the same event. A $35 transfer fee applies. Transfer of a member registration to a nonmember registration will be charged the difference in fees. 

Cancellations: Cancellation requests received 60 days or more prior to the start of the event will receive a full refund LESS a $75 administration fee. Cancellation requests received 30-59 days prior to the start of the event will receive a 50% refund. No refunds will be issued for cancellation requests received less than 30 days prior to the start of the event. Virtual training courses: No refunds for any reason will be issued after course instructions and materials have been sent to attendees.

  • IEST reserves the right to cancel courses, in which case registrants will receive a full refund of the tuition fee.
  • Program and instructor(s) are subject to change.
  • All registrations include lunch. 
  • Payment must accompany registration; there is no invoicing. IEST does not accept purchase orders as a method of payment.
  • All member dues must be current at the time of registration to qualify for the member rates.
  • All education training courses earn Continuing Education Units.
  • International attendees:  Full International Attendee details.

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