Cleanroom Design

Basics of Cleanroom Design, HVAC System Design, and Engineering Fundamentals 


This course will consist of two segments. The first will discuss the fundamentals of cleanrooms and HVAC systems design, including the classifications of cleanrooms, cleanroom ISO standards, design and testing guidelines by ASHRAE and NEBB, particulate sources from indoor and outdoor, and their impacts on cleanroom air cleanliness. Detailed discussions will cover airflow quantity, velocity, flow patterns and floor arrangement, key controlling variables on cleanroom’s air cleanliness, air shower, airlock and basic pressurization, HVAC, plumbing, fire protection, and process systems. Common cleanroom devices and equipment, architectural construction materials, cleaning procedures, testing standards, and other aspects will be highlighted.

The second segment will present existing and emerging design tools, approaches, and research findings in such areas as airflow rate determination by table method and modeling method; cleanroom’s real-time particle concentration monitoring, cleanroom’s response in challenges of varying airflow rate and particle generation (emission) rate; cleanroom’s recovery rate and recovery time after a major disturb or upset; demand flow control to conserve fan energy based on real-time room particle concentration; primary, secondary and tertiary air handling systems design strategies; airlock performance, CFD simulation, and finally the autonomous computer control of cleanroom ISO cleanliness class. etc.

Course outline     Course materials     Who Should Attend     Instructor     Next date and location     Pricing

Course outline

  1. Cleanroom Systems Design Fundamentals
    1. ISO Classifications & standards
    2. US cleanroom design guides and testing standard
    3. Particle sources from indoor and outdoor
    4. Airflow quantity and pattern and floor arrangement
    5. Contaminants (particle, microbial and chemical gas) migration from adjacent spaces
    6. Airlock and pressurization
    7. Basic plumbing, fire protection, and process systems
    8. Common devices and equipment
    9. Architectural construction materials, cleaning procedures, testing standards, and construction cost
  2. HVAC Modeling and Control
    1. Airflow modeling
    2. Demand flow control to conserve fan energy
    3. Primary, secondary, and tertiary air handling systems design strategies to achieve stable, efficient and tight indoor conditions
    4. Airlock performance
    5. CFD simulation
    6. Autonomous computer control of cleanroom ISO cleanliness class


Course materials

  • Copy of IEST-RP-CC012.3: Cleanroom Design
  • Copy of PowerPoint presentation in course binder

Continuing Education Units: .6 CEUs


Wei Sun

Wei Sun served as IEST Society President in 2016-2017, and Technical Vice President (Contamination Control) in 2013-2016, he has been the chair of WG-CC012 that is responsible for the new edition of RP-CC012.3 (Considerations in Cleanroom Design), and now leading the group working on the new RP-CC012.4 Edition.

Sun also has served as the Chair of ASHRAE Technical Committee TC9.11 (Clean Spaces) from 2007 to 2010, a voting member of ASHRAE TC9.10 (Laboratory Systems) and TC9.6 (Healthcare Facilities). He is an ASHRAE Fellow and an ASHRAE Distinguished Lecturer since 2008. In addition to his design expertise for large cleanroom, lab, and healthcare projects; he has been serving as a Principal Investigator for many governmental research projects, over a dozen of technical articles have been published. Recently he published a new technical book (426 pages) called “ASHRAE Design Guide for Cleanrooms”.

Furthermore, Sun is an ISO 14644 standards’ USA delegate for Working Group 4 (cleanroom design and construction) and Working Group 16 (energy conservation in cleanrooms). Sun recently has been serving as the chairperson of NEBB’s Cleanroom Performance Testing (CPT) Standard Committee and developing a new cleanroom testing standard for NEBB.       

He has been invited to provide numerous technical speeches and training courses for private US industries, governmental agencies, national, and international conferences.


Who should attend?

I need to learn more about cleanroom HVAC systems because:

  • I am a cleanroom design engineer from an architectural or engineering firm
  • I am a cleanroom design/build contractor
  • I am a cleanroom research professional
  • I am a cleanroom product sales engineer
  • I am a cleanroom facility engineer/manager
  • I am a cleanroom quality control engineer/manager


Next date and location

July 14, 2021
9:30 a.m. - 5:00 p.m. Central Time
Early-bird discount ends May 14. Use coupon code 7EB21BCRD to save 10% off your registration.
Online registration closes July 12.

Corporate Sponsors

Thank you to our the support from our Corporate Sponsors

Presidential Level